The replication, maintenance and transcription of the genome require an array of protein machines including polymerases, helicases, translocases, nucleases, recombinases and topoisomerases, often functioning as components of multi-protein complexes. Machines on Genes II will bring together scientists with an interest in multi- and inter-disciplinary approaches for unravelling the anatomy, architecture and mechanisms of these remarkable molecular machines. The conference will cover topics in DNA replication, recombination, repair and transcription and will showcase the latest work of world leaders in the fields of structural biology, chemical biology and novel biophysical methods including single-molecule detection.
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